USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P30086 USC-OGP 2-DE database:  P30086 P30086 General information about the entry View entry in simple text format Entry name PEBP1_HUMAN Primary accession number P30086 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=HCNPpp; AltName: Full=Neuropolypeptide h3; AltName: Full=Prostatic-binding protein; AltName: Full=Raf kinase inhibitor protein; Short=RKIP; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP;. Gene name Name=PEBP1 Synonyms=PBP, PEBP Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1053: pI=7.35; Mw=20527 Cross-references UniProtKB/Swiss-Prot P30086; PEBP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PEBP1_HUMAN Primary accession number P30086 Secondary accession number(s) B2R4S1 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 182) Name and origin of the protein Description RecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=HCNPpp; AltName: Full=Neuropolypeptide h3; AltName: Full=Prostatic-binding protein; AltName: Full=Raf kinase inhibitor protein; Short=RKIP; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP; Gene name Name=PEBP1 Synonyms=PBP, PEBP Encoded on Name=PEBP1; Synonyms=PBP, PEBP Keywords 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Disulfide bond; Lipid-binding; Nucleotide-binding; Phosphoprotein; Protease inhibitor; Reference proteome; Serine protease inhibitor. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL D16111; BAA03684.1; -; mRNA EMBL X75252; CAA53031.1; -; mRNA EMBL X85033; CAA59404.1; -; mRNA EMBL AK311927; BAG34868.1; -; mRNA EMBL CH471054; EAW98122.1; -; Genomic_DNA EMBL BC008714; AAH08714.1; -; mRNA EMBL BC017396; AAH17396.1; -; mRNA EMBL BC031102; AAH31102.1; -; mRNA EMBL S76773; AAD14234.1; -; mRNA CCDS CCDS9187.1; -; . PIR I53745; I53745; . RefSeq NP_002558.1; NM_002567.3; . UniGene Hs.433863; -; . PDB 1BD9; X-ray; 2.05 A; A/B=1-187 PDB 1BEH; X-ray; 1.75 A; A/B=1-187 PDB 2L7W; NMR; -; A=1-187 PDB 2QYQ; X-ray; 1.95 A; A=1-187 PDBsum 1BD9; -; . PDBsum 1BEH; -; . PDBsum 2L7W; -; . PDBsum 2QYQ; -; . ProteinModelPortal P30086; -; . SMR P30086; -; . BioGrid 111076; 40; . DIP DIP-44269N; -; . IntAct P30086; 10; . MINT MINT-5002544; -; . STRING 9606.ENSP00000261313; -; . MEROPS I51.002; -; . iPTMnet P30086; -; . PhosphoSitePlus P30086; -; . SwissPalm P30086; -; . BioMuta PEBP1; -; . DOSAC-COBS-2DPAGE P30086; -; . OGP P30086; -; . REPRODUCTION-2DPAGE IPI00219446; -; . REPRODUCTION-2DPAGE P30086; -; . SWISS-2DPAGE P30086; -; . UCD-2DPAGE P30086; -; . EPD P30086; -; . MaxQB P30086; -; . PaxDb P30086; -; . PeptideAtlas P30086; -; . PRIDE P30086; -; . TopDownProteomics P30086; -; . Ensembl ENST00000261313; ENSP00000261313; ENSG00000089220; . GeneID 5037; -; . KEGG hsa:5037; -; . UCSC uc001twu.2; human; . CTD 5037; -; . DisGeNET 5037; -; . GeneCards PEBP1; -; . HGNC HGNC:8630; PEBP1; . HPA CAB009906; -; . HPA CAB013493; -; . HPA HPA008819; -; . MIM 604591; gene; . neXtProt NX_P30086; -; . OpenTargets ENSG00000089220; -; . PharmGKB PA32968; -; . eggNOG KOG3346; Eukaryota; . eggNOG COG1881; LUCA; . GeneTree ENSGT00840000129869; -; . HOGENOM HOG000237655; -; . HOVERGEN HBG008165; -; . InParanoid P30086; -; . OMA SIEWEGC; -; . OrthoDB EOG091G0KH6; -; . PhylomeDB P30086; -; . TreeFam TF315074; -; . Reactome R-HSA-5674135; MAP2K and MAPK activation; . Reactome R-HSA-5675221; Negative regulation of MAPK pathway; . Reactome R-HSA-6802946; Signaling by moderate kinase activity BRAF mutants; . Reactome R-HSA-6802948; Signaling by high-kinase activity BRAF mutants; . Reactome R-HSA-6802949; Signaling by RAS mutants; . Reactome R-HSA-6802952; Signaling by BRAF and RAF fusions; . Reactome R-HSA-6802955; Paradoxical activation of RAF signaling by kinase inactive BRAF; . SignaLink P30086; -; . SIGNOR P30086; -; . ChiTaRS PEBP1; human; . EvolutionaryTrace P30086; -; . GeneWiki Phosphatidylethanolamine_binding_protein_1; -; . GenomeRNAi 5037; -; . PRO PR:P30086; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000089220; -; . CleanEx HS_PEBP1; -; . ExpressionAtlas P30086; baseline and differential; . Genevisible P30086; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0019899; F:enzyme binding; IPI:UniProtKB; . GO GO:0008429; F:phosphatidylethanolamine binding; TAS:ProtInc; . GO GO:0019901; F:protein kinase binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . Gene3D 3.90.280.10; -; 1; . InterPro IPR008914; PEBP; . InterPro IPR001858; Phosphotidylethanolamine-bd_CS; . Pfam PF01161; PBP; 1; . SUPFAM SSF49777; SSF49777; 1; . PROSITE PS01220; PBP; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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